Bud blast can happen to any species of orchid but Phalaenopsis are usually the most susceptible to this issue. Some skin diseases have no anatomic changes; these include the bizarre "aquagenic pruritus" ( see also aquagenic urticaria), in which contact with water at any temperature is followed by intense itching; some neuropeptide in the epidermis must be involved. There are close to 300 different varieties of enzymatic disorders that have been classified into 5 main groups according to their relationship to red blood cells and the premature destruction of red blood cells (hemolysis).

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